10 Best Medical Cannabis Strains to Treat Anxiety

Medical Cannabis is an effective treatment for Anxiety, and you will find its mention in ancient Indian medical literature, which says that cannabis helped people to deliver from worries and care. Modern day research tells us that the relationship between medical marijuana and anxiety treatment is bit more complex. It is true that medical cannabis is effective to reduce anxiety, but reports also show trend that frequent marijuana users have higher level of anxiety.

Anxiety Disorders – What Are They?

Anxiety disorders are expressed in many forms. All of which involves excess amount of worrying and uneasiness, apprehensions and fear. Some common forms include:–

Anxiety is more of a natural occurrence for people who suffer from severe impairment from the worries. Approximately, 18 percent of Americans and 14 percent of Europeans suffer from some form of anxiety disorder.

How is Medical Marijuana going to help?

Studies have shown that an endocannabinoid system plays a major role in anxiety. Cannabinoid receptors serve as the binding site for a high concentration of cannabinoids in certain parts of the human brain responsible for anxiety. It includes areas of the amygdala and hypothalamus.

Recent studies shows patients experience higher level of anxiety when cannabinoid receptors get blocked by drugs such as rimonabant. Regular cannabis users report that medical marijuana helps reduce their anxiety levels drastically. Research shows that endocannabinoid system plays a role in the extinction of bad memories. This explains why medical marijuana is prescribed to PTSD patients.

Interestingly, paranoia and anxiety attacks are some of the most commonly reported. Studies reveal a complex link between cannabinoids. Side effects of marijuana use on anxiety depend on the dosage taken as well as a type of cannabinoids present.


Effect of THC on Anxiety

Studies conducted on both animals and humans reveal a surprising relationship between THC and anxiety disorders. THC has very different effects on anxiety levels depending on the dosage of medical marijuana. THC acts to decrease anxiety with lower doses and increases anxiety with higher doses. On the other hand, experts are of the opinion that pure THC fails to show the effects of marijuana accurately. Cannabis contains more than 60 different cannabinoids. Marijuana also contains a compound called cannabidiol (CBD), several of which are of significant interest in the treatment of anxiety disorders.


Effect of CBD on Anxiety

THC acts mainly on the CB1 receptors found in high concentrations throughout the brain. Studies have shown that CBD plays a major role in regulating anxiety. This research suggests that CBD is a more effective treatment for anxiety than THC. The first study on CBD effect on anxiety was published in 1982. This study showed that CBD could regulate anxiety provoked by THC among eight healthy test subjects. Thus, marijuana rich in CBD may be a better option to relieve patients from anxiety. In 2011, researchers at the University of Sao Paulo in Brazil did two interesting experiments with CBD and anxiety. In the first experiment, 10 medical marijuana patients were given a 400mg dose of CBD. Then a public speaking test was administered to induce anxiety and compare the results to a control group. A similar study involved 24 patients and a 600 mg dose. The results showed that a single dose of CBD takes 90 minutes to reduce anxietyand discomfort during speech delivery.

Looking for the Right Medical Cannabis Strain

After conducting a number of studies, results seem to suggest that certain compounds in medical marijuana have an anti-anxiety effect both for healthy individuals and patients suffering from anxiety disorders. Hundreds of Americans are using medical marijuana to treat symptoms of anxiety each day. However, the search for a strain is a personal journey. Breeders have created hundreds of strains, so which can be the perfect one for anxiety requires human clinical trials. But that is impossible under current federal policy. However, 2.2 million medical cannabis patients in US are conducting trials of their own and sharing their info at websites such as Leafly.com and StickyGuide.com.

Many of the patients are of a mindset that any ol’ strains will do, and the genetic background does not matter. For people without consistent legal access to cannabis, the discussion is often only academic.

If you have access to a variety of cannabis strains, then we suggest try several to see their effect on you first. The chemical profile of the strains differs largely not just from strain to strain, but from grower to grower. We encourage you to look beyond the THC content of a strain.You may find a rich composition of cannabinoids and terpenes perfect for your condition.

Top 10 Medical Cannabis Strains effective to Treat Anxiety Disorders

Depending on the nature of symptoms, you will find strains offering different solutions. Grassmatch presents to you top 10 must try Medical strains to treat anxiety, in no particular order.

    1. Amnesia Haze
      • It comes in two main varieties – more sedative indicas and more energetic sativas. (Sativasare broadly recommends for anxiety as they cause euphoria.Patients differ in their reaction)
      • Amnesia Haze is an 80-20 sativa-dominant hybrid, winning 16 Cannabis Cups.
      • It is the perfect blend of sativas from Jamaica, Laos, Hawaii and Afghani.
      • You can enjoy a fresh, fruity flavor of lemon and citrus
      • It brings head high that breaks up negative thought patterns


    1. Mazar
      • It came second in High Tines’ 1999 Cannabis Cup Winner for the indica strain and was originally named Afghani Skunk.
      • It was renamed to Mazar in 1997
      • This strain has arrived from an area in the Mazar-i-Sharif region in Afghanistan and is of particular appeal to the indica lovers
      • This strain tastes like hash, fruit, citrus, and flowers
      • The strains has strong calming qualities
      • Recommended for medical marijuana patients who require muscle relaxation or looking for a good night sleep.


    1. Crimea Blue
      • Combination of genes from the Ukrainian Hash and Blueberry strains often noted for their complexity
      • It tastes like cheese, sour fruits, spices, and hash and delivers a high that may promote creativity
      • Tends to deliver a mind-altering Sativa-type high, often followed by “couch-lock” and sleep
      • Medicinal values of the strain include treatment to muscle-spasms for multiple sclerosis patients and pain reduction for neuropathy suffered by HIV/AIDS patients

crimea blue

    1. Green Crack
      • Allegedly named by Snoop Dogg, this is popular in SoCal and is in the process of being re-branded as Green Dragon
      • Descended from two genetic lineages – its sativa line descended from Skunk #1 and 75% of the indica variety came from an Afghani Strain
      • A tangy, fruity flavor redolent of Mango, Green Crack is more a preferred daytime medication for medical marijuana patients
      • You will enjoy a cerebral effect that provides creative energy without any fatigue

green crack

    1. Sour Diesel
      • It is a more sativa-dominant version of Chemdawg popularized on the East Coast, noted strongly for their smell and flavor
      • The strain has a very high THC content responsible for head high giving euphoria
      • Fast-acting strain that delivers energizing, dreamy cerebral effects
      • Has a pungent flavor of lemon-fuel and pine


    1. Trainwreck
      • A mind-bending hybrid with potential sativa effects that hits like a freight train
      • A pure mix of Mexican and Thai sativas with Afghani indicas
      • Passes on a sweet lemon and spicy aroma
      • It is quick to bring a surge of euphoria giving rise to creativity and happiness


    1. Island Sweet Skunk
      • Sometimes called Sweet Island Skunk
      • Pungent and tropical
      • 70 percent sativa blend of Skunk#1 (Mexico, Columbia, and Afghanistan) and an unknown sativa
      • Perky upbeat followed up by a soft body buzz
      • Often has an aroma those of grapefruit
      • Some of the varieties of Island Sweet Skunk have a high CBD content to help patients treat anxiety, inflammation, and muscular spasms

island sweet skunk

    1. Bubba Kush
      • Bubba Kush originally a cross between OG Kush and a parent that is the cross between West Coast Dog and Old World Kush.
      • Green House Seeds also cultivates a unique blend of Bubble Gum and Kush
      • It has a sweet, earthy indica strain with genetics tracing back to Hindukush Strains
      • Its main effect is focused on the head, well it is not long before the buzz reaches the rest of the body
      • It is perfect as the evening time medication


    1. Super Silver Haze
      • Super Silver Haze was the first prize winner at the High Times Cannabis Cup in 1997, 1998 and 1999
      • A multiple generation of Haze combines and crosses with some Northern Lights #5 and Skunk#1
      • It is a beautiful and a sticky sativa blend that a sweet, spicy and earthy aroma
      • Boost an energetic, long lasting body high
      • Patients report mostly uplifting, psychedelic effects, and it is great for a long walk

Super silver haze

    1. AK-47
      • Came into being in 1992 by Serious Seeds and has won numerous Cannabis Cup awards for its high THC content
      • It is a blend of Colombian, Mexican, Thai and Afghani varieties bringing together the blend of both their flavors and effects
      • The scent is sour and earthy, and their sweet floral notes can be fully experienced in the taste
      • This sativa dominant hybrid strain delivers long-lasting and steady head buzz that gives your mentally active and engaged in creative and social activities

AK 47

We have performed our survey as per the reviews published in

We would like our readers to pour their thoughts and opinions about various strains they have used or have been using to reduce anxiety.

Whatever your preference, you need to choose the right medical marijuana caregiver to supply your medication. And we know it’s a tough challenge. But, we like to take up challenges. So finding medical marijuana caregiver in Michigan is easy at Grassmatch.

At our legal marketplace, you will get a list of local caregivers with whom you can communicate safely to get the right strain to treat your anxiety related disorders. And guess what it’s all FREE! So Hurry up, Join Now!


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